Here's what obesity researchers Jules Hirsch, Jeffrey Friedman, and Rudolph Leibel did: They bred mice that were unable to produce leptin. The result? Those mice all ate nonstop and became obese!
How does this help us humans who want to lose weight? We need to be sure we are producing enough leptin to let us know when we are satiated.
When do humans produce leptin? During sleep - and not just the moment we fall asleep, but only after about 6 or 7 hours of sleep. If you are sleep deprived, your supply of leptin may be reduced and you will feel hungry and eat more.
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