Phendimetrazine is also in the phenethylamine
class of drug
and is sold under the brand names Bontril, Plegine, Prelu-2, and X-Trozine.
Phendimetrazine was approved by the FDA in1976 and is meant for the first few weeks of
a diet and exercise program for the obese.
Phendimetrazine stimulates the central nervous system,
just as phentermine does,
but
it has more of a noticeable stimulating
effect than does phentermine. Phendimetrazine is available
as time-release capsules and as a result, patients
report having more energy throughout the day, even when they are not active. Phendimetrazine does not have the same level of cravings control
as phentermine.
Phendimetrazine could be prescribed for the first few weeks of a diet to assist with
initial weight loss, after which the patient could be prescribed phentermine to assist
with continuing appetite control. Both
of
these drugs could play a role in an overall plan of weight reduction that includes diet and exercise.
Phendimetrazine can increase blood pressure and is therefore not recommended for people with high blood pressure. Other side effects include dizziness, insomnia, headache, dry mouth, and
constipation. Phendimetrazine can also become
habit forming if used beyond the recommended first few weeks
of
a diet. Used alone, phendimetrazine has not been reported to cause the same types of lung or heart valve problems that Fen- phen or Redux did. However, if phendimetrazine is combined with other appetite suppressants,
specifically phentermine, or is used in higher than recommended
doses or for too long, lung and heart valve problems may occur.
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